A worldwide e-Infrastructure for NMR and structural biology

Postdoctoral Position in Structural Biology of Disordered Proteins by NMR

A 2-year post-doctoral position funded by the EpiGenMed Labex program is available to work in the “Highly Flexible Proteins” group lead by Pau Bernadó at the Centre de Biochime Structurale (CBS) in Montpellier (France).

Project: The project focuses in deciphering the structural bases of the regulation of Nuclear Receptor gene transcription by Intrinsically Disordered co-regulator proteins. This is an interdisciplinary project that will be performed in collaboration with other groups at the CBS including the crystallography of Nuclear Receptors (William Bourguet) and molecular simulations (Alessandro Barducci) groups. Nuclear Magnetic Resonance (NMR) will be the main experimental technique used to develop the project. NMR will be combined with Small-Angle X-ray Scattering (SAXS), computational approaches and other biophysical techniques.

Candidate: The successful candidate should have a PhD in chemistry, biology or physics and a solid background in solution state biomolecular NMR spectroscopy. Experience in protein expression, purification and biophysical characterization is strongly recommended. Knowledge in other techniques such as SAXS and computational methods will be favourably considered.

Environment: The laboratory hosts high-field state-of-the-art NMR spectrometers for biomolecular applications: A 800 MHz and a 700 MHz both equipped with cryoprobes and a 600 MHz. In addition to NMR, the CBS has an outstanding infrastructure covering all techniques for structural biology and biophysics including X-ray crystallography, cryo-electron microscopy, advanced fluorescence and super-resolution microscopes, single-molecule manipulation, molecular and cell biology, and high-performance computation.

Montpellier is a major biology area with a focus on basic research, biomedicine, plant biology and environmental science. Its science drive, the beauty of the region, its high quality of life, and the short commute to other major regional research areas (Paris, Barcelona, Toulouse, Marseille) make it an ideal destination for scientists from all over the world.

Application: Applications and informal queries about the project and the lab should be addressed to Pau Bernadó (pau.bernado@cbs.cnrs.fr). Interested candidates should send their CV, a cover letter describing their research interests and motivation, and the names of persons willing to write a recommendation letter.

Contacts

pau.bernado
pau.bernado@cbs.cnrs.fr

Cite WeNMR/WestLife

 
Usage of the WeNMR/WestLife portals should be acknowledged in any publication:
 
"The FP7 WeNMR (project# 261572) and H2020 West-Life (project# 675858) European e-Infrastructure projects are acknowledged for the use of their web portals, which make use of the EGI infrastructure and DIRAC4EGI service with the dedicated support of CESNET-MetaCloud, INFN-PADOVA, NCG-INGRID-PT, RAL-LCG2, TW-NCHC, SURFsara and NIKHEF, and the additional support of the national GRID Initiatives of Belgium, France, Italy, Germany, the Netherlands, Poland, Portugal, Spain, UK, South Africa, Malaysia, Taiwan and the US Open Science Grid."
 
And the following article describing the WeNMR portals should be cited:
Wassenaar et al. (2012). WeNMR: Structural Biology on the Grid.J. Grid. Comp., 10:743-767.

EGI-approved

The WeNMR Virtual Research Community has been the first to be officially recognized by the EGI.

European Union

WeNMR is an e-Infrastructure project funded under the 7th framework of the EU. Contract no. 261572

WestLife, the follow up project of WeNMR is a Virtual Research Environment e-Infrastructure project funded under Horizon 2020. Contract no. 675858

West-Life