A worldwide e-Infrastructure for NMR and structural biology

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Structural and biophysical methods for biological macromolecules in solution EMBO Global Exchange Lecture Course

19 -- 26 January 2014,  São Paulo, Brazil


The main objective of the Course is to teach the young PhD students and postdocs from all areas of biology the methods applicable to study biological macromolecules in solution. We aim at a comprehensive coverage of the field including the major structural and biophysical techniques employed for the characterization of high and low resolution structure and structural transitions, macromolecular complex
formation, protein folding and stability, protein-protein and protein-ligand interactions and enzymatic mechanisms. The Course will include lectures on small-angle X-ray and neutron scattering (SAXS/SANS), nuclear magnetic resonance (NMR), static and dynamic light scattering (SLS/DLS), analytical ultracentrifugation (AUC), differential and isothermal calorimetry (DSC/ITC) and spectroscopic approaches.
Bioinformatic tools to analyze protein-protein interactions will be considered, and the joint use of the solution characterization methods with the major non-solution structural techniques including macromolecular crystallography (MX) and electron microscopy (EM) will be covered. Special attention will be paid to interdisciplinary approaches, where the synergistic use of complementary techniques leads to a comprehensive description of macromolecular systems.

The course will be held at the Adma Jafet Auditorium at Institute of Physics of the University of Sao Paulo (IFUSP), Brazil.

A maximum of 50 participants will be selected to attend the course.
A registration fee of 50 Euro will be requested from the academic participants covering the event materials, lodging and local meals.
Applicants from industry are expected to pay a 1000 Euro fee.

The Course is oriented towards applicants active in Structural Biology, mostly late Ph.D. students and early post-docs but more senior scientists,
depending on circumstances, could also participate. Students working in Brazil or Brazilian students working abroad will be given preference but all applications are welcome.

Application deadline for the Course: October, 15th, 2013

Cite WeNMR/WestLife

Usage of the WeNMR/WestLife portals should be acknowledged in any publication:
"The FP7 WeNMR (project# 261572), H2020 West-Life (project# 675858) and the EOSC-hub (project# 777536) European e-Infrastructure projects are acknowledged for the use of their web portals, which make use of the EGI infrastructure with the dedicated support of CESNET-MetaCloud, INFN-PADOVA, NCG-INGRID-PT, TW-NCHC, SURFsara and NIKHEF, and the additional support of the national GRID Initiatives of Belgium, France, Italy, Germany, the Netherlands, Poland, Portugal, Spain, UK, Taiwan and the US Open Science Grid."
And the following article describing the WeNMR portals should be cited:
Wassenaar et al. (2012). WeNMR: Structural Biology on the Grid.J. Grid. Comp., 10:743-767.


The WeNMR Virtual Research Community has been the first to be officially recognized by the EGI.

European Union

WeNMR is an e-Infrastructure project funded under the 7th framework of the EU. Contract no. 261572

WestLife, the follow up project of WeNMR is a Virtual Research Environment e-Infrastructure project funded under Horizon 2020. Contract no. 675858